About the brain and spine

Introduction to the Brain and Spine

The human brain and spine, collectively known as the central nervous system (CNS), are sophisticated structures that regulate numerous functions in our bodies. Here’s a basic understanding of these vital components.

The Brain

The brain is the control center of the body and is responsible for processing sensory information, coordinating movement, regulating bodily functions, and enabling cognition, emotion, and consciousness.

The brain is divided into several key areas:

  • Cerebrum: The largest part, responsible for higher brain functions like thinking, learning, consciousness, and emotions. It’s divided into two halves or ‘hemispheres’ and further subdivided into four main ’lobes’: frontal, parietal, temporal, and occipital, each with specific functions.
  • Cerebellum: Located at the back of the brain, it coordinates voluntary movements, balance, and muscle coordination.
  • Brainstem: Connects the cerebrum and cerebellum to the spinal cord and controls functions vital to life, like breathing, heart rate, and blood pressure.

The Spine

The spine, also known as the vertebral column or spinal column, is a robust structure that provides support to the body and houses the spinal cord.

The spine is composed of 33 individual bones called ‘vertebrae’, stacked one on top of another. These vertebrae are grouped into different regions:

  • Cervical: The top 7 vertebrae that form the neck.
  • Thoracic: The next 12 vertebrae connected to the rib cage.
  • Lumbar: 5 vertebrae in the lower back.
  • Sacral and coccygeal: The remaining vertebrae fused together to form the sacrum and the coccyx (tailbone).

The spinal cord, protected by the spine, is the primary pathway transmitting messages between the brain and the rest of the body.

Blood Supply and Neurovascular Conditions

The brain and spine require a constant supply of oxygen and nutrients, provided by a network of blood vessels, including arteries and veins. Any abnormality in these vessels can lead to neurovascular conditions. These could range from aneurysms (bulges in blood vessels that can rupture) and arteriovenous malformations (tangles of blood vessels causing disrupted blood flow), to dural arteriovenous fistulas (abnormal connections between vessels) and strokes (where blood flow to a part of the brain is cut off).

The Nervous System

Broadly, the human nervous system can be divided into two main components: the Central Nervous System (CNS) and the Peripheral Nervous System (PNS).

The CNS, as mentioned earlier, is comprised of the brain and spinal cord. It is the central processing unit of the body, interpreting incoming sensory information and orchestrating the body’s response.

The PNS, on the other hand, consists of the vast network of nerves that extend from the spinal cord to the rest of the body. It serves as a communication bridge between the CNS and the body’s organs, muscles, and skin. The PNS is further divided into the sensory (or afferent) division, which sends information to the CNS, and the motor (or efferent) division, which sends information from the CNS to muscles and glands.

Meninges and Cerebrospinal Fluid

The brain and spinal cord are protected by a three-layered membrane known as the meninges. From the outermost layer inward, these layers are the dura mater, arachnoid mater, and pia mater.

Cerebrospinal Fluid (CSF) circulates within and around the brain and spinal cord, providing additional cushioning, delivering nutrients, and removing waste. CSF is produced in the brain’s ventricles and is crucial for maintaining the brain’s buoyancy and for acting as a shock absorber.

Understanding Neurovascular Terminology

As you explore information about neurovascular conditions, you may come across some specific terminology. Here are some basic terms and their meanings:

  • Neurovascular: Pertains to the nervous system (neuro-) and blood vessels (vascular).

  • Intracranial: Refers to something located or occurring within the skull. Intracranial neurovascular conditions affect the blood vessels in the brain.

  • Subarachnoid Space: The space between the arachnoid mater and pia mater (layers of the meninges) where the cerebrospinal fluid circulates and the major blood vessels supplying the brain are located.

  • Haemorrhage: Bleeding or the abnormal flow of blood. In the context of neurovascular conditions, it often refers to bleeding in the brain caused by ruptured aneurysms or arteriovenous malformations.

  • Ischemia: A condition in which there is insufficient blood flow to tissues, leading to a lack of oxygen that can cause damage or dysfunction. In the brain, ischemia can result in a stroke.

  • Embolisation: A therapeutic procedure used to treat some neurovascular conditions by blocking blood flow to a specific area.

Imaging of the Brain and Spine

For diagnosing and managing neurovascular conditions, several imaging techniques are commonly used. Here’s a quick rundown of what they are:

  • MRI (Magnetic Resonance Imaging): Uses a strong magnetic field and radio waves to produce detailed images of the brain and spine. Useful for visualizing soft tissues and detecting abnormalities.

  • CT (Computed Tomography): Employs a series of X-ray images taken from different angles around the body, which are then processed by a computer to produce cross-sectional images. Often used for quickly visualizing bleeding in the brain.

  • DSA (Digital Subtraction Angiography): A more invasive procedure that involves injecting a contrast dye into blood vessels and then taking X-ray images. It provides detailed views of blood vessels in the brain and spinal cord.

This basic understanding of the brain and spine will serve as a foundation to learn more about specific neurovascular conditions and their treatment options, as well as to facilitate more informed discussions with your healthcare provider.


Article author
Dr Jeremy Lynch, Consultant neurointerventional radiologist, Kings College Hospital, United Kingdom